Pharmaceutical Dissolution Testing – Sampling and Assay

Date	Oct 16, 2018
Time	03:00 PM EDT
Cost	$200.00
Online

Pharmaceutical dissolution testing plays an important part in the quality control of solid oral drug products. This webinar will help attendees to avoid common mistakes in dissolution sampling and assay that might decrease confidence in the data or lead to a failure to comply with compendial requirements.

Areas Covered in the Session :
– Dissolution testing and drug product safety/efficacy
– Dissolution sampling

• Compendial requirements
  • Time interval
  • Sampling position
  • Filtration
• Observations
• Loss of analyte through adsorption
• Choice of sample filter
• Is centrifugation acceptable?
• Dissolution medium replacement – when and how
• Automation

– Dissolution assay

• Choice of assay/detection technique
  • UV
  • HPLC
• Correcting for sample volume in the assay calculation
  • No dissolution medium replacement
  • Dissolution medium replacement

Who Should Attend:

• Analytical Management Teams
• Method Development Teams
• Quality Control Departments
• Quality Assurance Departments